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pentobarbital will lessen the level or influence of abemaciclib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Keep away from or Use Alternate Drug. Coadministration of abemaciclib with robust CYP3A4 inducers decreases plasma focus of abemaciclib and its metabolites.In retrospect, many of the fears and hopes that coalesced round the NuTe